Discriminant Analysis and Its Application in DNA Sequence Motif Recognition

نویسنده

  • Michael Q. Zhang
چکیده

Identification of functional motifs in a DNA sequence is fundamentally a statistical pattern recognition problem. Discriminant analysis is widely used for solving such problems. This paper will review two basic parametric methods: LDA (linear discriminant analysis) and QDA (quadratic discriminant analysis). Their usage in recognition of splice sites and exons in the human genome will be demonstrated.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

A MODEL FOR THE BASIC HELIX- LOOPHELIX MOTIF AND ITS SEQUENCE SPECIFIC RECOGNITION OF DNA

A three dimensional model of the basic Helix-Loop-Helix motif and its sequence specific recognition of DNA is described. The basic-helix I is modeled as a continuous ?-helix because no ?-helix breaking residue is found between the basic region and the first helix. When the basic region of the two peptide monomers are aligned in the successive major groove of the cognate DNA, the hydrophobi...

متن کامل

Video-based face recognition in color space by graph-based discriminant analysis

Video-based face recognition has attracted significant attention in many applications such as media technology, network security, human-machine interfaces, and automatic access control system in the past decade. The usual way for face recognition is based upon the grayscale image produced by combining the three color component images. In this work, we consider grayscale image as well as color s...

متن کامل

Sequence Analysis and Phylogenetic Profiling of the Nonstructural (NS) Genes of H9N2 Influenza A Viruses Isolated in Iran during 1998-2007

The earliest evidences on circulation of Avian Influenza (AI) virus on the Iranian poultry farms date back to 1998. Great economic losses through dramatic drop in egg production and high mortality rates are characteristically attributed to H9N2 AI virus. In the present work non-structural (NS) genes of 10 Iranian H9N2 chicken AI viruses collected during 1998-2007 were fully sequenced and subjec...

متن کامل

Face Recognition by Cognitive Discriminant Features

Face recognition is still an active pattern analysis topic. Faces have already been treated as objects or textures, but human face recognition system takes a different approach in face recognition. People refer to faces by their most discriminant features. People usually describe faces in sentences like ``She's snub-nosed'' or ``he's got long nose'' or ``he's got round eyes'' and so like. These...

متن کامل

A Multi Linear Discriminant Analysis Method Using a Subtraction Criteria

Linear dimension reduction has been used in different application such as image processing and pattern recognition. All these data folds the original data to vectors and project them to an small dimensions. But in some applications such we may face with data that are not vectors such as image data. Folding the multidimensional data to vectors causes curse of dimensionality and mixed the differe...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Briefings in bioinformatics

دوره 1 4  شماره 

صفحات  -

تاریخ انتشار 2000